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ClinicalOncologyNKT-Cell Lymphoma

Tislelizumab and Zeprumetostat Show Promise in NK/T-Cell Lymphoma Phase Ib/II Trial

The ongoing phase Ib/II trial of tislelizumab and zeprumetostat represents a significant development in the treatment of relapsed or refractory NK/T-cell lymphoma. Positive trial outcomes could reshape treatment guidelines and enhance competitive positioning in this therapeutic area.

Published: June 19, 2026
Updated: June 19, 2026
Author: Humanexa Intelligence
Therapeutic area: Oncology / NK/T-Cell Lymphoma
Asset: tislelizumab
Trial SummaryCLN

Phase II

Oncology / NK/T-Cell Lymphoma

Status

Active

Signal Score

8.4

Signal assessment

Signal strength

high

Confidence level

high

Signalhigh
Confidencehigh

Strategic implication

The ongoing phase Ib/II trial of tislelizumab and zeprumetostat represents a significant development in the treatment of relapsed or refractory NK/T-cell lymphoma. Positive trial outcomes could reshape treatment guidelines and enhance competitive positioning in this therapeutic area.

Why it matters

The ongoing phase Ib/II trial of tislelizumab and zeprumetostat represents a significant development in the treatment of relapsed or refractory NK/T-cell lymphoma. Positive trial outcomes could reshape treatment guidelines and enhance competitive positioning in this therapeutic area.

What changed

Trial Update

Analysis

A phase Ib/II trial is evaluating the combination of tislelizumab and zeprumetostat in relapsed or refractory NK/T-cell lymphoma, focusing on determining the recommended phase II dose and assessing efficacy.

The ongoing phase Ib/II trial of tislelizumab and zeprumetostat represents a significant development in the treatment of relapsed or refractory NK/T-cell lymphoma. Positive trial outcomes could reshape treatment guidelines and enhance competitive positioning in this therapeutic area.

Key milestones include the determination of the recommended phase II dose and the results of the objective response rate at week 12.

Related companies & assets

Assets

  • tislelizumab →

Sources & Humanexa intelligence

Source links

  • Tislelizumab and Zeprumetostat Show Promise in NK/T-Cell Lymphoma Phase Ib/II Trial ↗

Related Humanexa pages

  • Tislelizumab and Zeprumetostat Show Promise in NK/T-Cell Lymphoma Phase Ib/II Trial →

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